You can choose which command groups are available in a perspective. Command groups contribute menu items, toolbar buttons and key bindings, all of which run commands. Making a command group unavailable in a perspective removes these methods of running commands. Making a command group available makes it possible for these methods to be used, however they can be turned on and off with more fine-grained control via the Menu Visibility and Tool Bar Visibility tabs of the Customize Perspective dialog.
To configure command group availability:
Changing where perspectives open
Specifying the default perspective
Saving a user defined perspective